Sister chromatid exchanges and structural chromosome aberrations in relation to age and sex

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1982 English Publisher:Springer Science and Business Media LLCJournal:Human Genetics, volume 62, pages 305-309 (issn: 0340-6717, eissn: 1432-1203,

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Authors: K, Hedner; B, Högstedt; A M, Kolnig; E, Mark-Vendel; B, Strömbeck; F, Mitelman;

doi: 10.1007/bf00304544

pmid: 7166305

Sister chromatid exchanges and structural chromosome aberrations in relation to age and sex

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Abstract

Sister chromatid exchanges (SCE) and structural chromosome aberrations were analyzed in peripheral blood lymphocytes of 100 individuals, and correlated to age and sex. No correlation was found between the frequency of SCE and age, but older individuals had significantly more structural aberrations than younger. Females had significantly more SCE as well as structural chromosome aberrations than males. The positive correlations of SCE and structural aberrations to age and sex were also significant when these factors, as well as smoking habits, were taken into consideration in an analysis of covariance.

Related Organizations

Lund University
Sweden

Keywords

Adult, Chromosome Aberrations, Male, Adolescent, Smoking, Age Factors, Middle Aged, Sex Factors, Humans, Female, Crossing Over, Genetic, Sister Chromatid Exchange, Aged

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