Chromosomes in acute leukemia
Copyright policy )Chromosomes in acute leukemia
The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromosomal abnormalities were found in 50 patients (72%). Chromosomes 8,21,5,7,11, and 19 were preferentially involved in the abnormalities, both in ANLL and in ALL. A high incidence of the characteristic rearrangement t(8;21) was noted in AML: (in 6 of 22 AMP patients). An identical reciprocal translocation--t(4;11)--was seen in 4 out of 34 ALL patients.
Adult, Chromosome Aberrations, Chromosomes, Human, 6-12 and X, Genetic Markers, Male, Leukemia, Adolescent, Chromosomes, Human, 19-20, Infant, Middle Aged, Chromosome Banding, Leukemia, Lymphoid, Child, Preschool, Chromosomes, Human, 21-22 and Y, Humans, Female, Chromosomes, Human, 4-5, Chromosome Deletion, Child, Aged
Adult, Chromosome Aberrations, Chromosomes, Human, 6-12 and X, Genetic Markers, Male, Leukemia, Adolescent, Chromosomes, Human, 19-20, Infant, Middle Aged, Chromosome Banding, Leukemia, Lymphoid, Child, Preschool, Chromosomes, Human, 21-22 and Y, Humans, Female, Chromosomes, Human, 4-5, Chromosome Deletion, Child, Aged
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