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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Kybernetikarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Kybernetik
Article . 1974 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
zbMATH Open
Article
Data sources: zbMATH Open
Kybernetik
Article . 1975
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The mechanism of impulse generation in excitable cells

Authors: Chaplain, R. A.;

The mechanism of impulse generation in excitable cells

Abstract

Auf der Grundlage eines verallgemeinerten Membranmodelles fur den Ionentransport wird eine Beziehung zwischen Ionenleitwert und Membranpotential als modellmasige Bedingung fur die Impulsauslosung definiert. Hierdurch ist es moglich, die Impulsform und die Umsetzungskennlinie zwischen Eingangssignal und abgegebener Impulsfrequenz fur verschiedene erregbare Membranen quantitativ vorauszusagen. Wahrend die Kinetik des Natriumkanals die eigentliche Bedingung fur die Impulsauslosung bestimmt, beeinflust der Kaliumkanal hauptsachlich die Impulspause. Eine Analyse der Impulsauslose-Kennlinie und der Empfindlichkeit des Membransystems fur Anderungen im Gleichgewichtspotential, in der lonenleitfahigkeit oder der Membrankapazitat zeigt charakteristische Unterschiede fur impulsubertragende Membranen wie dem Axon des Riesentintenfisches und dem Ranvierschen Schnurring und der impulskodierenden Membran des Zellsomas von isolierten Schneckenneuronen. Die Muskelzellmembran nimmt eine Zwischenstellung ein. Fur Membranen mit echten Kodiereigenschaften liegt das Maximum der Impulsauslosecharakteristik erheblich hoher als die stationare Leitwert-Potential-Beziehung. Dadurch ist eine stabile Impulsabgabe uber einen grosen Bereich des Eingangssignals moglich. Bei impulsleitenden Strukturen ist dieser Bereich erheblich kleiner. Wenn als Resultat einer langsamen Natriuminaktivierung der Anstieg der Impulsauslosecharakteristik so flach wird, das sie nicht mehr von der stationaren Leitwert-Potential-Kennlinie geschnitten wird, kann keine stabile Impulsfolge mehr ausgelost werden.

Related Organizations
Keywords

Ion Exchange, Cell Membrane Permeability, Xenopus, Animals, Synaptic Transmission, General biology and biomathematics, Membrane Potentials

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
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