Extrachromosomal inheritance in Schizosaccharomyces pombe
Copyright policy )Extrachromosomal inheritance in Schizosaccharomyces pombe
In contrast to the wild-type, mutant [ANTr8] is able spontaneously to throw off stable respiratory deficient mutants. The frequency of these mutants is considerably enhanced by treatment with ethidium bromide (EB) or the azo-dye Janus green (JG). An unstable cell state with a petite-like phenotype is found in both mutant [ANTr8] and wild-type after EB-treatment. However, only in the mutant is this unstable cell state followed by the appearance of stable respiratory deficient (RD) mutants. Formation of microcolonies is observed both in [ANTr8] and wild-type. RD mutants were isolated after EB treatment. Three of them (mit-12, mit-25, and mit-30) were analyzed and mit-25 characterized in more detail.
Extrachromosomal Inheritance, Mitosis, Haploidy, DNA, Mitochondrial, Diploidy, Electron Transport, Ascomycota, Ethidium, Mutation, Schizosaccharomyces, Coloring Agents
Extrachromosomal Inheritance, Mitosis, Haploidy, DNA, Mitochondrial, Diploidy, Electron Transport, Ascomycota, Ethidium, Mutation, Schizosaccharomyces, Coloring Agents
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