
doi: 10.1007/bf00276348
pmid: 845508
An important role of myoglobin in red muscle is to facilitate the diffusion of oxygen for metabolism. We consider a model for muscle respiration in which the oxygen consumption is of a Michaelis-Menten form. The resulting mathematical model is solved in two different ways with two different boundary conditions. The first uses the singular perturbation method of Murray (1974), while the second, which gives another justication of the simpler procedure, is a direct numerical computation of the full problem. The oxygen tension and saturation are often small. For realistic values of the Michaelis-MENTEN CONSTANT the oxygen tension, the saturation and the radius of the region in which the oxygen tension is negligibly small can be calculated using the constant consumption model of Murray (1974), with corrected boundary conditions (those for a Stefan problem), which in certain circumstances mardedly affect the solution.
Diffusion, Kinetics, Oxygen Consumption, Boundary value problems for ordinary differential equations, Myoglobin, Muscles, Models, Biological, General biology and biomathematics
Diffusion, Kinetics, Oxygen Consumption, Boundary value problems for ordinary differential equations, Myoglobin, Muscles, Models, Biological, General biology and biomathematics
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