Biocenversion of cyclohexene derivatives

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1984 English Publisher:Springer Science and Business Media LLCJournal:Applied Microbiology and Biotechnology, volume 20, pages 310-312 (issn: 0175-7598, eissn: 1432-0614,

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Authors: I. Belič; E. Ghera; H. E. Gottlieb; A. Plemenitaš;

doi: 10.1007/bf00270591

Biocenversion of cyclohexene derivatives

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Abstract

Bioconversion of new methylcyclohexene derivatives with bulky side chains ending in aromatic or heteroaromatic rings by Streptomyces natalensis and Mycobacterium smegmatis results in monohydroxylation of the cyclohexene ring. Further oxidation of the hydroxyl group into a keto group is effected only with M. smegmatis. The synthesis of the substrates and proof of the structure of the products is given in detail.

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