Interspecific transformation of rifampicin resistance in the genus Bacillus

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1973 English Publisher:Springer Science and Business Media LLCJournal:Molecular and General Genetics MGG, volume 120, pages 151-155 (issn: 0026-8925, eissn: 1432-1874,

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Authors: N, Harford; M, Mergeay;

doi: 10.1007/bf00267243

pmid: 4631265

Interspecific transformation of rifampicin resistance in the genus Bacillus

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Abstract

Transfer of resistance to rifampicin, a genetic determinant for RNA polymerase, was tested by transformation between B. subtilis as recipient and eight other Bacillus species as DNA donors. Seven of these donors effected transformation of rifampicin as well as erythromycin resistance, and cotransfer of these linked markers was also found in the interspecific crosses. The results extend the concept of a region of gene conservation in this genus.

Keywords

Genetics, Microbial, Transformation, Genetic, Bacillus, Drug Resistance, Microbial, Rifampin, Bacillus subtilis, Erythromycin

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