Myocardiotoxicity of 5 Fluorouracil

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1988 English Publisher:Springer Science and Business Media LLCJournal:Intensive Care Medicine, volume 14, pages 429-430 (issn: 0342-4642, eissn: 1432-1238,

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Authors: B, Coronel; O, Madonna; A, Mercatello; A, Caillette; J F, Moskovtchenko;

doi: 10.1007/bf00262901

pmid: 3403776

Myocardiotoxicity of 5 Fluorouracil

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Abstract

We report a case of specific myocardiotoxicity due to 5 F.U. not previously described in man. A 41-year-old man was admitted to the ICU for heart and renal failure, appearing 24 h after 5 days treatment with 5 F.U. and cis-platinum. Dopamine was necessary to maintain blood pressure. Two-D echocardiography and a right heart catheterisation confirmed the alteration of myocardial contractility. After 2 weeks a complete cardiac recovery occurred.

Related Organizations

Hospices Civils de Lyon
France
Hôpital Édouard-Herriot
France

Keywords

Adult, Cardiomyopathy, Dilated, Male, Humans, Fluorouracil, Laryngeal Neoplasms

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