Epidermal growth factor receptor in adenocarcinoma of the kidney

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1989 English Publisher:Springer Science and Business Media LLCJournal:Urological Research, volume 17 (issn: 0300-5623, eissn: 1434-0879,

Copyright policy )

Authors: Ambs KE; Takahashi A; Hering F; Costa S; Huber PR;

doi: 10.1007/bf00262605

pmid: 2788950

Epidermal growth factor receptor in adenocarcinoma of the kidney

- Summary
- Subjects
- Metrics

Abstract

Epidermal growth factor receptor (EGF-R) was estimated in Hypernephroma by saturation analysis using 125-I EGF as ligand. Tissue levels of this oncogene related protein were increased five-fold (24 to 99 fmol/mg protein) in comparison with the surrounding tumor free tissue (3 to 18 fmoles/mg protein). There was no apparent correlation to the stage of tumor growth or tumor differentiation and there was no correlation of EGF serum levels with tumor growth. EGF serum levels in the tumor patients did not exceed levels in control patients.

Keywords

Adult, Male, Epidermal Growth Factor, Tumor Necrosis Factor-alpha, Middle Aged, Kidney Neoplasms, ErbB Receptors, Humans, Female, Carcinoma, Renal Cell, Aged

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	20
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%