
doi: 10.1007/bf00223521
pmid: 6358857
A review is presented on 1) the autonomous nature of mammalian cell cytoplasm and 2) the cytoplasmic modification of nuclear gene expression. Topics include a discussion of cytoplasmic suppression of tumorigenicity. It is proposed that alterations in DNA methylation patterns may be a possible mechanism to explain cytoplasmic modification of nuclear gene expression.
Cell Nucleus, Cytoplasm, Cell Differentiation, DNA, Neoplasms, Experimental, Hybrid Cells, Methylation, Rats, Mice, Gene Expression Regulation, Animals, Humans
Cell Nucleus, Cytoplasm, Cell Differentiation, DNA, Neoplasms, Experimental, Hybrid Cells, Methylation, Rats, Mice, Gene Expression Regulation, Animals, Humans
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