
doi: 10.1007/bf00219349
pmid: 1312991
A polymerase chain reaction (PCR)-based assay has been designed that detects the presence of the human signal recognition particle receptor (SRPR) gene in inter-species somatic cell hybrids. By using hybrids containing various fragments of chromosome 11q, SRPR has been mapped to a chromosomal region flanked by the 11q23 and 11q24 breakpoints associated with the constitutional and neuroepithelioma (11;22) translocations, respectively.
Electrophoresis, Agar Gel, Base Sequence, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 22, Molecular Sequence Data, Chromosome Mapping, DNA, Hybrid Cells, Polymerase Chain Reaction, Translocation, Genetic, Oligodeoxyribonucleotides, Ribonucleoproteins, Humans, Neuroectodermal Tumors, Primitive, Peripheral, Signal Recognition Particle
Electrophoresis, Agar Gel, Base Sequence, Chromosomes, Human, Pair 11, Chromosomes, Human, Pair 22, Molecular Sequence Data, Chromosome Mapping, DNA, Hybrid Cells, Polymerase Chain Reaction, Translocation, Genetic, Oligodeoxyribonucleotides, Ribonucleoproteins, Humans, Neuroectodermal Tumors, Primitive, Peripheral, Signal Recognition Particle
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