A new EcoRI polymorphism at the D21S13 locus
Copyright policy )A new EcoRI polymorphism at the D21S13 locus
The D21S13 locus has shown linkage to a gene for familial Alzheimer disease (FAD) on chromosome 21 (St. George-Hyslop et al. 1987). The limited informativeness of probes for this locus have hindered precise mapping of the FAD locus and analysis of nonallelic heterogeneity in FAD (Schellenberg et al. 1988; St. George-Hyslop et al. 1987). We describe a new EcoRI polymorphism at the D21S13 locus that may be useful for the further study of FAD families.
- University of California, Los Angeles United States
- Cedars-Sinai Medical Center United States
Male, Blotting, Southern, Alzheimer Disease, Chromosomes, Human, Pair 21, Chromosome Mapping, Humans, Female, Polymorphism, Restriction Fragment Length, Deoxyribonuclease EcoRI, Pedigree
Male, Blotting, Southern, Alzheimer Disease, Chromosomes, Human, Pair 21, Chromosome Mapping, Humans, Female, Polymorphism, Restriction Fragment Length, Deoxyribonuclease EcoRI, Pedigree
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