A flow network is a system of mutually intersecting holes in a plate or an assembly of plates. The flow at each intersection is characterized by a collision of two flow streams, resulting in complex flow patterns through the downstream holes. In the case of multiple intersections, the flow is periodically disrupted at each succeeding intersection, thus preventing the formation of a fully-developed flow through the holes. An experimental study is presented in this paper to determine flow characteristics in flow networks with various geometry. The intersecting pressure loss coefficient which represents the performance of flow networks is defined and its magnitude empirically determined as functions of geometric and flow conditions. A method is developed to measure the ramming loss in an intersection tube. Flow visualization by means of hydrogen bubble method is applied to observe flow patterns and mixing behavior in the flow network. A physical model is developed to predict the intersection pressure loss in flow networks.