Biotransformation of 2-acetylthiophene by micromycetes

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1991 English Publisher:Springer Science and Business Media LLCJournal:Applied Microbiology and Biotechnology, volume 34 (issn: 0175-7598, eissn: 1432-0614,

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Authors: Fran�oise Seigle-Murandi; Serge Krivobok; R�gine Steiman; Georges-Andr� Thiault; Jean-Louis Benoit-Guyod;

doi: 10.1007/bf00180566

Biotransformation of 2-acetylthiophene by micromycetes

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Abstract

The biotransformation of 2-acetylthiophene by 800 strains of micromycetes has been investigated. Among them, 460 strains have been selected on solid media and cultivated in a liquid synthetic medium. Of these, 106 strains were able to completely deplete 2-acetylthiophene with or without production of intermediary metabolites. 2-Thienylglyoxylic acid was not detected but 72 strains produced 2-thiophenecarboxylic acid. Among them, eight strains have been selected for further optimization of this bioconversion.

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Grenoble Alpes University
France

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