On Codon reassignment

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1995 English Publisher:Springer Science and Business Media LLCJournal:Journal of Molecular Evolution, volume 41 (issn: 0022-2844, eissn: 1432-1432,

Copyright policy )

Authors: S, Osawa; T H, Jukes;

doi: 10.1007/bf00170679

pmid: 7666454

On Codon reassignment

- Summary
- Subjects
- Metrics

Abstract

Schultz and Yarus (J. Mol. Biol. 235:1377-1380, 1994) have proposed that reassignment of codons in the genetic code passes through a stage in which the codons are ambiguously translated. In contrast we state that such ambiguity would be deleterious, and that, to be reassigned, a codon, together with the tRNA that translates the codon, must first disappear from coding sequences, after which a tRNA appears with a mutated anticodon, and this enables the codon to reappear with a changed meaning. In the case of a stop codon, the relevant release factor must change so as to recognize it.

Related Organizations

Space Sciences Laboratory
United States
University of California, Berkeley
United States

Keywords

RNA, Transfer, Genetic Code, Codon

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	30
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%