
doi: 10.1007/bf00163915
pmid: 1940662
Equilibria and convergence of gene frequencies are studied in the case of a diallelic X-linked locus under the influence of selection and mutation. The model used is that of an infinite diploid population with nonoverlapping discrete generations and random mating. It is proved that if the mutation rates and fitnesses are constant and the mutation rates are less than one-third, then global convergence of gene frequencies to equilibria occurs. The phase portraits of the dynamical system describing the change of allelic frequencies from one generation to the next are determined. Convergence of gene frequencies is monotone from a certain generation on if every other generation is skipped. In the case without mutation, our proof of this monotone convergence simplifies G. Palm's original proof.
Male, non-overlapping discrete generations, X Chromosome, Genetic Linkage, selection, phase portraits, inheritance dynamics of human hemophilia, Hemophilia A, Problems related to evolution, diallelic \(X\)-linked locus, Gene Frequency, infinite diploid population, Humans, global convergence of gene frequencies, Selection, Genetic, Alleles, Models, Genetic, mutation rates, random mating, Models, Theoretical, equilibria, allelic frequencies, Mutation, Female, Genetics and epigenetics, mutation
Male, non-overlapping discrete generations, X Chromosome, Genetic Linkage, selection, phase portraits, inheritance dynamics of human hemophilia, Hemophilia A, Problems related to evolution, diallelic \(X\)-linked locus, Gene Frequency, infinite diploid population, Humans, global convergence of gene frequencies, Selection, Genetic, Alleles, Models, Genetic, mutation rates, random mating, Models, Theoretical, equilibria, allelic frequencies, Mutation, Female, Genetics and epigenetics, mutation
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