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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Documenta Ophthalmol...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Documenta Ophthalmologica
Article . 1992 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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Stargardt's disease

Family studies
Authors: M, Mäntyjärvi; K, Tuppurainen;

Stargardt's disease

Abstract

Three families including seven members with Stargardt's disease were examined. In addition to the affected family members, 43 of the relatives had an eye examination. In one family, there was a consanguineous marriage to be found. The heredity was most probably autosomal recessive in all of the three families. The ages of the seven patients with Stargardt's disease varied from 13 to 50 years, visual acuities from 0.05 to 1.0, and refraction from -8.5 to +2.25 D. In fundus, absent foveal reflex, atrophic macular spots and yellow perimacular flecks could be observed; one patient had also yellow flecks in the peripheral retina. In the visual fields, a central scotoma was found in five patients. Dark adaptation was abnormal in three patients and electroretinogram in one patient. All of the patients had defective red colour vision. In the fluoresceinangiogram, hyperfluorescent macular spots and dark choroid could be observed. The ophthalmological findings are discussed comparing them to the earlier observations of this disease.

Related Organizations
Keywords

Adult, Male, Color Perception Tests, Adolescent, Visual Acuity, Dark Adaptation, Middle Aged, Refractive Errors, Pedigree, Macular Degeneration, Electroretinography, Humans, Female, Fluorescein Angiography

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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Top 10%
Average
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