
During apoptosis, nuclear pores undergo strong modifications, which are described here in five different apoptotic models. Conventional electron microscopy, supported by freeze-fracture analysis, showed a constant migration of nuclear pores towards the diffuse chromatin areas. In contrast, dense chromatin areas appear pore-free and are frequently surrounded by strongly dilated cisternae. A possible functional significance of this pore behaviour during apoptosis is discussed.
570, Mice, Inbred BALB C, Nuclear Envelope, nuclear pores; apoptosis, Mast-Cell Sarcoma, Apoptosis, Thymus Gland, Cell Line, Leukemia, Lymphoid, Mice, Microscopy, Electron, Leukemia, Myeloid, Tumor Cells, Cultured, Animals, Freeze Fracturing, Humans
570, Mice, Inbred BALB C, Nuclear Envelope, nuclear pores; apoptosis, Mast-Cell Sarcoma, Apoptosis, Thymus Gland, Cell Line, Leukemia, Lymphoid, Mice, Microscopy, Electron, Leukemia, Myeloid, Tumor Cells, Cultured, Animals, Freeze Fracturing, Humans
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