AbstractRecent discoveries seem to indicate a catastrophic history of terrestrial evolution, explicable in terms of Oort cloud disturbance by molecular clouds in the Galactic disc. The problem of Oort cloud replenishment thus assumes considerable significance and reasons are given for supposing comet exchange takes place during actual penetration of molecular clouds. The number density of comets in molecular clouds, thereby implied, seems to suggest primary condensations of ≤103km in a dense precursor state of spiral arms. If chemical and/or isotopic signatures of comets should indicate an extra-Solar System source, the theory of terrestrial catastrophism may place new constraints on our understanding of the origin of molecular clouds.