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Understanding Left Ventricular Function

Authors: B. Leone; P. Foëx;

Understanding Left Ventricular Function

Abstract

The characteristics of cardiac muscle contraction and relaxation have been extensively investigated using isolated heart muscle preparations. In such preparations, the effects of changes in preload (Starling’s law of the heart) and in contractility have been clearly defined, and many indices of contractility described. These indices, extensively validated in isolated heart muscle preparations, have been used to assess the inotropic state of the intact heart. However, the intact heart is not a band of muscle lifting a weight, it is a muscle pump ejecting a viscous fluid (the blood) into viscoelastic systems (the systemic and pulmonary circulations). In order to characterize the behaviour of the cardiac pump, the dynamic relationships between pressure and dimensions may be more appropriate than the analysis of pressure alone.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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Average
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