In 1959 two Swedish researchers Jerker Porath and Per Gustaf Flodin reported their findings in Nature in a paper entitled “Gel Filtration: a method for desalting and group separation” (1). They described a method based on a column procedure which they claimed was “similar” to chromatography. The stationary phase they used was a cross linked dextran which within the year was launched by Pharmacia as a product called Sephadex®. Today, the paper is considered a classic in the methodology of biochemistry and Sephadex, after 29 years, is still used and referenced throughout the world (2).