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Amide-Adducts in Atherosclerosis

Name: Amide-Adducts in Atherosclerosis
Creator: Michitaka Naito
Keywords: 0301 basic medicine, Inflammation, 0303 health sciences, 03 medical and health sciences, Oxidative Stress, 13. Climate action, Lipoproteins, Humans, Lipid Peroxidation, Atherosclerosis

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 11 Dec 2013 English Publisher:Springer Netherlands

Authors: Michitaka Naito;

doi: 10.1007/978-94-007-7920-4_8

pmid: 24374921

Amide-Adducts in Atherosclerosis

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Abstract

Too many hypotheses in the etiology of atherosclerosis have been proposed. Classically, lipid insudation hypothesis by Virchow and thrombogenic hypothesis by Rokitansky are famous. However, in the recent progress in the area of atherosclerosis, the response-to-injury hypothesis by Ross (Ross R Glomset JA, N Engl J Med 295:369-377, 420-425, 1976; Ross R, Arteriosclerosis 1:293-311, 1981; Ross R, N Engl J Med 314:488-500, 1986; Ross R, Nature 362:801-809, 1993; Ross R, N Engl J Med 340:115-126, 1999) has been the leading one. In this review, however, the author focuses to the recent debate on the role of oxidative modification of atherogenic lipoproteins.

Related Organizations

Sugiyama Jogakuen University
Japan

Keywords

Inflammation, Oxidative Stress, Lipoproteins, Humans, Lipid Peroxidation, Atherosclerosis, Amides, Oxidation-Reduction

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