MCM Structure and Mechanics: What We Have Learned from Archaeal MCM

Minichromosome maintenance (MCM) complexes have been identified as the primary replicative helicases responsible for unwinding DNA for genome replication. The focus of this chapter is to discuss the current structural and functional understanding of MCMs and their role at origins of replication, which are based mostly on the studies of MCM proteins and MCM complexes from archaeal genomes.

Related Organizations

University of California System
United States
University of Southern California
United States

Keywords

DNA Replication, DNA, Archaeal, Minichromosome Maintenance Proteins, Genome, Archaeal, Archaeal Proteins, Archaea

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