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The Story of Nifedipine

Authors: S. Kazda;

The Story of Nifedipine

Abstract

Nifedipine is one of the most successful compounds in pharmacology. The drug has substantially improved the therapeutic armamentarium of cardiovascular medicine. Because of its well-defined mechanism and high specificity of calcium antagonistic action, nifedipine has become an important tool in physiological and pathophysiological research into the role of calcium ions, and the pathogenesis of cardiovascular and numerous other diseases. Undoubtedly, nifedipine’s success has done much to stimulate new ways of thinking in medical sciences. Is nifedipine itself also an intellectual product of systematic scientific thinking? What premises led to the discovery of calcium antagonism as a therapeutic principle and nifedipine as a prominent drug in this field?

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
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