Despite the fact that the cutaneous malignancies managed by Mohs’ micrographic surgery (MMS) often prove quite invasive and extensive, and that many of the patients are elderly, the procedure is amazingly free of complications. This is true even when a multidisciplinary approach under general anesthesia is required either to rid the patient of his tumor and/or to reconstruct the surgical defect [1]. Many of the potential complications of MMS are not unique but are common to all surgical procedures involving the skin. These have been reviewed by others [2] and are also discussed elsewhere in this volume. Because other authors discuss the complications associated with the repair of surgical defects, and because these are no more likely or different in the MMS patient, I omit these from my discussion.