Metabolism of Isoflurane

Name: Metabolism of Isoflurane
Creator: V. Hempel
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 01 Jan 1986Publisher:Springer Berlin Heidelberg

Authors: V. Hempel;

doi: 10.1007/978-3-642-71230-2_5

Metabolism of Isoflurane

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Abstract

Isoflurane is a halogenated methyl-ethyl-ether. The ethyl group is protected against degradation by its trifluorocarbon end and the difluoral methyl group seems to be stable. Therefore, the results of Halsey’s group [2], who failed to detect any hepatic extraction of isofluorane in minipigs exposed to subanesthetic concentrations, were taken as evidence for its resistance to biodegradation.

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