Squamous cell carcinoma (SCC) is an invasive epithelial malignancy that arises from the prickle–squamous cell layers of the epidermis and shows keratinocytic differentiation. It is capable of metastasis to regional lymph nodes and is potentially lethal. SCC was first distinguished from basal cell carcinoma by Kompecher in 1902 [1]. The terms “squamous cell epithelioma,” “epidermoid carcinoma,” “epithelioma spinocellular,” “prickle cell epithelioma,” and “spinalioma” have all been used in the literature, but “squamous cell carcinoma” is the preferred terminology.