Nerve repositioning is the subject of discussion in this chapter. In brief, in this procedure an ostectomy of the lateral mandibular cortex is performed, the inferior alveolar nerve (IAN) is lateralized outside of the inferior alveolar canal (IAC), then dental implants are placed under direct visualization with protection of the IAN as inferior as the basal bone, and may even engage the inferior cortex of mandible. Eventually the IAN is passively positioned aside the implants with or without an interpositional graft material. In this method, implants of greater length may be placed and even bicortical mandibular anchorage is possible. Treatment duration is shortened compared to other techniques utilizing bone grafting. However, this technique temporarily weakens the mandible and may predispose it to mandibular fracture [1–3]. Anatomic reconstruction of the lost alveolar bone cannot be achieved by this method [1, 2]. But, by using longer implants after nerve repositioning, resistance to occlusal forces increases and compatibility between the implant and the prosthesis improves [2]. Postoperative sensory disturbances are among the most important complications and considerations with this technique.