Administer prophylactic antibiotics. Ensure that vitamin K given to neonates. Ensure pathologist available; the biopsy must be sent fresh. The procedure can be performed without general anaesthetic. Neonates should be placed in the lithotomy position. Older children should be placed on the left lateral side, knees bent. Anatomy of suction biopsy forceps (Fig. 1) Blunt, hollow tube, side hole 1 cm from tip Concealed blade within shaft of instrument Marks on side of tube show level of biopsy Side port for attaching suction tubing 5- to 20-ml syringe to apply suction Variation Disposable capsules and blade (Fig. 2) In-line manometer to record suction