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pmid: 21104393
Since the discovery of the endocannabinoid system, a growing body of psychiatric research has emerged focusing on the potential role of this system in schizophrenia. On the basis of earlier epidemiological studies and results from animal models, endocannabinoids and their relation to symptoms are considered in clinical studies as well as in post-mortem analyses of cannabinoid CB₁ receptor densities. A possible neurobiological mechanism for the deleterious influence of cannabis use in schizophrenia is discussed, involving the disruption of endogenous cannabinoid signalling and function.
Disease Models, Animal, Receptor, Cannabinoid, CB1, Cannabinoids, Dopamine, Cannabinoid Receptor Modulators, Schizophrenia, Animals, Brain, Humans, Models, Biological
Disease Models, Animal, Receptor, Cannabinoid, CB1, Cannabinoids, Dopamine, Cannabinoid Receptor Modulators, Schizophrenia, Animals, Brain, Humans, Models, Biological
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 0 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |