Upper gastrointestinal bleeding (UGIB) is a life-threatening condition that accounts for a significant number of hospitalizations, leading to considerable morbidity, mortality, and resource utilization. UGIB has a multitude of causes, with peptic ulcer disease and varices being the most common, and disproportionately affects the elderly with a higher mortality among these patients. The majority of UGIB patients do not require intervention; therefore, identifying patients at risk of rebleeding or mortality is the goal. Aggressive resuscitation and timely endoscopy for localization of the bleeding source are paramount to identify patients who do not stop bleeding and may require endoscopic, surgical, or angiographic intervention.