Context: Lack of volume in the back of the hands, evidencing bones, vessels, and tendons, is a very common complaint concerning this area. During the last decade, there have been significant advances in the technology embedded in hyaluronic acid (HA) products, as well as a refinement of application techniques that, together, permitted the HA to become a gold standard as a filling and volumizing agent for the face. After years of expertise with these products, we expanded the indications for extra-facial areas. The back of the hands is one of these interesting areas to be treated by HA.