Pharmacokinetics and Pharmacodynamics of Fibrinolytic Agents

Name: Pharmacokinetics and Pharmacodynamics of Fibrinolytic Agents
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 01 Jan 2015 English Publisher:Springer International Publishing

Authors: H. David Rodriguez; Carlos Jerjes-Sánchez;

doi: 10.1007/978-3-319-19707-4_2

Pharmacokinetics and Pharmacodynamics of Fibrinolytic Agents

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Abstract

In this chapter, the historical development, as well as, pharmacokinetics and pharmacological properties of the more frequently used fibrinolytic agents in pulmonary embolism patients, namely streptokinase, alteplase, and tenecteplase are analyzed. The historical development of the first-, second-, and third-generation fibrinolytics has been reviewed. Also, the first pulmonary embolism case using successful thrombolysis with streptokinase, rt-PA, alteplase, and TNK-t-PA is described.

Related Organizations

Monterrey Institute of Technology and Higher Education
Mexico
Hospital Zambrano Hellion
Mexico

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