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Groupwise Deformable Registration of Fiber Track Sets Using Track Orientation Distributions

Authors: Christiaens, Daan; Dhollander, Thijs; Maes, Frederik; Sunaert, Stefan; Suetens, Paul;

Groupwise Deformable Registration of Fiber Track Sets Using Track Orientation Distributions

Abstract

Diffusion-weighted imaging (DWI) and tractography allow to study the macroscopic structure of white matter in vivo. We present a novel method for deformable registration of unsegmented full-brain fiber track sets extracted from DWI data. Our method attempts to align the track orientation distributions (TODs) of multiple subjects, rather than individual tracks. As such, it can handle complex track configurations and allows for multi-resolution registration. We validated the registration method on synthetically deformed DWI data and on data of 15 healthy subjects, and achieved sub-voxel accuracy in dense white matter structures. This work is, to the best of our knowledge, the first demonstration of direct registration of probabilistic tractography data.

Country
Belgium
Related Organizations
Keywords

PSI_MIC, track orientation distribution, registration, diffusion-weighted imaging, tractography

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
Green