Structural biology techniques have greatly contributed to unveiling the interplay between molecular structure, physico-chemical properties, and biological function of viruses. In recent years, classic structural approaches are being complemented by single-molecule techniques such as atomic force microscopy and optical tweezers to study physical features of viral particles that are not accessible to classic structural techniques. Among these features are mechanical properties such as stiffness, intrinsic elasticity, tensile strength, and material fatigue. The field of virus mechanics is contributing to materials science by investigating some physical parameters of "soft" biological matter and biological nano-objects. Virus mechanics studies are also starting to unveil the biological implications of some physical properties of viruses and their contribution to virus function. Virus particles are subjected to internal and external forces and they may have adapted to withstand, and even use those forces. This chapter focuses on the mechanical properties of virus particles, their structural determinants, their use to study virus function, and some possible biological implications, of which several examples are provided.