Cephalopods are animals endowed with a high regenerative potential. They can regenerate missing or injured structures such as the cornea, the shell, the arms and tentacles and even peripheral nerves and brain centers. As much as regeneration and healing cannot be considered as pathologies sensu stricto, they are always accompanied by conditions such as inflammation, tissue degeneration and potentially by infection. No treatments are currently available for any of these cases. Although they often get resolved autonomously, the early identification and monitoring of post-traumatic events is fundamental in the context of animal welfare.