In this chapter, the method about selection of amine solvent for CO2 capture plant was proposed in order to improve the efficiency of the process. The properties of amines solvents related to CO2 capture were discussed in order to design the plant based on the selected amines. The physical properties (i.e. density, viscosity, specific heat capacity, Henry’s law constant, and diffusivity) are very key parameters for design of the plant or determination the performance of solvent. The measurement of those physical properties are also present in this chapter. Also, the present correlations for the experimental results of Henry’s law constant and the diffusivity are discussed. In addition, some chemical properties related to the reaction of amines and CO2 such as the solubility, reaction kinetics should be addressed before the further study. Those parameter determine the capacity of solvent or the reaction rate of the solvent, which are necessary for the process design or process stimulation. In order to understand the process of reaction, the ions speciation plots are studied by using the different methods, which are added in this chapter. The trend of the new solvent and the improvement of the current solvent are discussed in this chapter.