Animal models of neurodegenerative disease are excellent tools for studying pathogenesis and therapies including cellular transplantation. In this chapter, we describe different models of Huntington's disease and Parkinson's disease, stereotactic surgery (used in creation of lesion models and transplantation) and finally transplantation studies in these models.

Related Organizations

University of Cambridge
United Kingdom

Keywords

Cell- and Tissue-Based Therapy, Mice, Transgenic, Parkinson Disease, Disease Models, Animal, Mice, Huntington Disease, alpha-Synuclein, Animals, Humans, Drosophila, Caenorhabditis elegans, Zebrafish, Stem Cell Transplantation

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