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Antiviral Activity of Lactoferrin

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 01 Jan 1998 Italy Publisher:Springer US

Authors: VALENTI, PIERA; M. Marchetti; F. Superti; M. G. Amendolia; P. Puddu; S. Gessani; P. Borghi; +3 Authors

doi: 10.1007/978-1-4757-9068-9_23

pmid: 9781359

handle: 11590/114938 , 11573/83809

Antiviral Activity of Lactoferrin

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Abstract

In 1976, Matthews et al.19 reported the antiviral activity of milk proteins, underlining their possible clinical importance. Only recently, this effect has been ascribed mainly to lactoferrin (Lf). Lf was initially shown to exert a protective influence in mice infected with Friend leukemia virus15. Subsequently, a potent antiviral activity has been attributed to Lf, both in vitro towards cytomegalovirus (HCMV)9,7, herpes simplex virus (HSV)17, human immunodeficiency virus (HIV)7,29 and in vivo towards HSV-16 and HCMV25. Our groups provided evidence on the antiviral activity of Lf towards HSV-218, rotavirus28, and HIV22 infections (Table 1).

Country

Italy

Related Organizations

Keywords

Lactoferrin, Virus Diseases, Animals, Humans

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	71
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%