The investigation of the binding, dynamics and properties of peptides adsorbed on inorganic surfaces is an inherently multidisciplinary endeavor. This chapter is primarily aimed at new researchers in this field, to introduce the basic concepts that span physical chemistry, surface science, structural biology, computational techniques, and materials science; all of which are necessary for gaining a comprehensive overview of peptide-materials interfaces. What are the key insights that can be determined from these interfaces? Usually, this will comprise a blend of thermodynamics, kinetics and structural characterizations. Typically, we might wish to compare the binding strength of a peptide, and concomitantly, the structure(s) assumed by the peptide upon adsorption. We might also seek to characterize the surface diffusion, and/or aggregation (or assembly) of these surface-adsorbed biomolecules. These observations serve to facilitate connections between the composition and sequence of the peptide, and its behavior and properties at the interface. Such connections could be subsequently exploited in bioinformatics models to enable the prediction of new peptide sequences, with designed, predictable interfacial properties.