At the end of the day, single embryo transfer (SET) is not a big technical innovation, but rather more of an ideology, another way of defining success, not only through pregnancy rates in the fresh cycle. Successful implementation of SET requires that everybody involved in the IVF treatment perform at their best, and some authors claim that the degree of SET performed at a particular center is the best measure for performance of that center. Given that there are both pros and cons with SET, it is, however, likely that it will become more and more utilized as both patients and society realize the risk even with twins.