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Gene Expression Profiling in Melanoma

Name: Gene Expression Profiling in Melanoma
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 22 Jun 2013 Italy Publisher:Springer New York

Authors: Crispi S; Caputo E;

doi: 10.1007/978-1-4614-7357-2_36

handle: 20.500.14243/140898

Gene Expression Profiling in Melanoma

- Summary
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Abstract

One of the big challenges in cancer research is to identify genomic alterations responsible for genesis and progression of disease. Melanoma is one of the most difficult tumours to treat for its aggressiveness, strong therapeutic resistance and proclivity for late metastasis. Here we describe the new gene high-throughput technologies, microarray and next-generation sequencing (NGS), and their impact in melanoma research. We illustrate their use from the discovery of melanoma biomarkers and therapeutic targets to clinical applications including patients' classification and stratification.

Country

Italy

Related Organizations

National Research Council
Italy
Institute of Genetics and Biophysics
Italy

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	1
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average