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Gene-Environment Interactions

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article 01 Jan 2012Publisher:Springer US

Authors: Gang Zheng; Yaning Yang; Xiaofeng Zhu; Robert C. Elston;

doi: 10.1007/978-1-4614-2245-7_10

Gene-Environment Interactions

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Abstract

Gene-environment interactions are considered in Chap. 10, which focuses on a 2×2×2 table. The expressions of odds ratios for the genetic effect, the environmental factor effect, and the gene-environment interaction are given. More general cases for gene and environmental factors are briefly discussed. Three common tests for gene-environment interaction are studied, including the Score test, the likelihood ratio test (LRT) and the Wald test. Examples are given with detailed calculations.

Related Organizations

Case Western Reserve University
United States
University of Science and Technology of China
China (People's Republic of)

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