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Human Monoclonal Antibodies

Authors: Alan N. Houghton; Richard J. Cote;

Human Monoclonal Antibodies

Abstract

The monoclonal antibody technology has had a major impact on the serological and biochemical analysis of human tumor antigens. Monoclonal antibodies have rapidly led to the identification and characterization of a large number of antigenic determinants on cancer cells. To date, most of these monoclonal antibodies have been of mouse or rat origin. Antigens recognized by these reagents have therefore been defined generally by their immunogenicity in the mouse or rat, and they do not necessarily correspond to antigens that are immunogenic in humans.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
Related to Research communities
Cancer Research
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