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Rat-Rat Hybridoma Formation and Rat Monoclonal Antibodies

Authors: Hervé Bazin;

Rat-Rat Hybridoma Formation and Rat Monoclonal Antibodies

Abstract

The first model of monoclonal antibody-secreting hybridomas, developed by Kohler and Milstein (1), was a mouse system. It can be considered eminently successful, most likely because of its efficiency and extreme stability. If it is so successful, why develop another rodent model? There are, at least, three main reasons.

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    5
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
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