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Behavioral and Physical Activity Interventions for HAND

Authors: Montoya, Jessica L; Henry, Brook; Moore, David J;

Behavioral and Physical Activity Interventions for HAND

Abstract

Approximately 30-50% of persons living with HIV manifest some degree of neurocognitive impairment. Even mild-to-moderate forms of HIV-associated neurocognitive disorders (HAND) can result in difficulties with everyday functioning, such as suboptimal medication adherence and impaired driving. Despite the pervasive presence and consequences of HAND, there is a significant unmet need to develop effective behavioral strategies to reduce the incidence and consequences of HAND. Although there is an absence of evidence-based behavioral interventions specific to HAND, the literature reviewed in this chapter suggest the following modifiable lifestyle factors as intervention targets: physical activity, diet, sleep, and antiretroviral medication adherence. Adoption and maintenance of these healthy lifestyle factors may reduce inflammation and oxidative stress, which, in turn, may reduce the incidence and/or severity of HAND.

Country
United States
Keywords

Prevention (rcdc), Neurocognitive Disorders (mesh), HIV Infections, Neurodegenerative, Acquired Cognitive Impairment (rcdc), Antiretroviral therapy adherence, Clinical Research (rcdc), Cognition, Brain Disorders (rcdc), Psychology, Sleep (mesh), 32 Biomedical and Clinical Sciences (for-2020), Neurosciences (rcdc), Neurodegenerative (rcdc), Humans (mesh), 52 Psychology (for-2020), Clinical and Health Psychology, 3209 Neurosciences (for-2020), Physical Activity (rcdc), Mental Health, Infectious Diseases, HIV/AIDS, Sleep Research, Behavioral and Social Science (rcdc), Mental Health (rcdc), Exercise (mesh), Neurocognitive Disorders, 610, HIV Infections (mesh), Clinical Research, Behavioral and Social Science, 616, Acquired Cognitive Impairment, Humans, Sleep Research (rcdc), Exercise, Nutrition, HIV/AIDS (rcdc), Biomedical and Clinical Sciences, Physical activity, Prevention, Neurosciences, Physical Activity, Brain Disorders, Diet, Nutrition (rcdc), Infectious Diseases (rcdc), 5202 Biological psychology (for-2020), 5203 Clinical and Health Psychology (for-2020), Sexually Transmitted Infections, Biological psychology, Sleep, Sexually Transmitted Infections (rcdc)

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
8
Top 10%
Average
Average
Green