
Transition metal-catalyzed C–H bond functionalization has recently emerged as an indispensable tool for transforming otherwise unreactive C–H bonds. In addition to various strategies for ortho-selective functionalization via chelation assistance, organometallic C–H activation has recently enabled novel functionalizations of (hetero)arenes at remote meta- or para-positions. The meta- and para-selectivity was governed either by the inherent substrate structure or by the transition metal catalyst. Herein we summarize the rapid recent progress in meta- and para-selective aromatic C–H functionalization until May 2015.
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