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pmid: 15648175
Structural studies of foot-and-mouth disease virus (FMDV) have largely focused on the mature viral particle, providing atomic resolution images of the spherical protein capsid for a number of sero- and sub-types, structures of the highly immunogenic surface loop, Fab and GAG receptor complexes. Additionally, structures are available for a few non-structural proteins. The chapter reviews our current structural knowledge and its impact on our understanding of the virus life cycle proceeding from the mature virus through immune evasion/inactivation, cell-receptor binding and replication and alludes to future structural targets.
Integrins, Foot-and-Mouth Disease Virus, Virus Assembly, Receptors, Virus, Capsid Proteins, Genome, Viral, Viral Nonstructural Proteins, Heparan Sulfate Proteoglycans
Integrins, Foot-and-Mouth Disease Virus, Virus Assembly, Receptors, Virus, Capsid Proteins, Genome, Viral, Viral Nonstructural Proteins, Heparan Sulfate Proteoglycans
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 72 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |