Leiomyomas may be treated with UAE followed by myomectomy in a scheduled or unscheduled manner. UAE may be scheduled immediately prior to myomectomies if the patient has large fibroids or pedunculated or subserosal myomas, or wishes to maintain an intact uterus for the possibility of pregnancy within a short time window. UAE may be beneficial in these instances because it reduces blood loss in removal of large fibroids and prevents fibroid recurrence. Patients who benefit from the combination of these procedures include young patients with a high risk of recurrence and patients wanting to achieve pregnancy immediately after 6 months of the surgery. Unscheduled myomectomies occur if the UAE fails to relieve symptoms, if prolapsed of a submucous myoma occurs, or in the event of fibroid necrosis.