This paper introduces the invited session of “Intelligent Agents and their Applications” being presented at the 10th International Conference on Knowledge-Based and Intelligent Information and Engineering Systems. This session concentrates on discussing Intelligent Agents and uses some applications to demonstrate the theories reported. An update on last years session [1] is included to report on several key advances in technology that further enable the ongoing development of multi-agent systems. A brief summary of the impediments presented to researchers is also provided to highlight why innovation must be used to sustain the evolution of Artificial Intelligence. This year a variety of challenges and concepts are presented, together with a collection of thoughts about the direction and vision of Intelligent Agents ands their Applciations.